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Posted: Thursday, January 11, 2018 12:48 AM

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Job Description:

Acceleron is a Cambridge-based, clinical-stage biopharmaceutical company dedicated to the discovery, development, and commercialization of therapeutics to treat serious and rare diseases. The Company’s leadership in the understanding of TGF-beta biology and protein engineering generates innovative compounds that engage the body’s ability to regulate cellular growth and repair.

Acceleron focuses its research and development efforts in hematologic, neuromuscular, and pulmonary diseases. In hematology, the Company and its global collaboration partner, Celgene, are developing luspatercept for the treatment of chronic anemia in myelodysplastic syndromes, beta-thalassemia, and myelofibrosis. Acceleron is also advancing its neuromuscular franchise with two distinct Myostatin+ agents, ACE-083 and ACE-2494, and a pulmonary program with a Phase 2 trial of sotatercept planned in pulmonary arterial hypertension.


What’s in it for you?

We are seeking talented and passionate individuals who thrive in a dynamic, fast-paced, team-oriented and collaborative environment to be part of our success. You will work closely with various members of the Preclinical team and will contribute to investigations on new and ongoing research projects to establish therapeutic potential of drug candidates. You will use your assay development expertise to support our efforts in the therapeutic area of pulmonary hypertension.


What will you be doing?


• Working closely with group members to contribute to in vivo model systems and techniques to evaluate efficacy and mechanism of action of protein therapeutic agents
• Conducting experiments to support research projects in related therapeutic areas
• Working with cross functional drug development group to bring research stage molecules to clinical development
• Independently reviewing current scientific literature for advances in hypertension and related fields
• Attending and contributing to team meetings
• Maintaining sustained lines of communication across research teams



Job Requirements

• B.S. or equivalent degree in cell biology or related field, with a minimum of 3 years of experience
• Excellent rodent handling skills
• Prior experience using in vivo models to study pulmonary or cardiorenal disease as well as hands-on experience in cardiac and vascular catheterization would be a plus
• Prior experience in conducting experiments to evaluate drug efficacy, including measuring hemodynamic parameters and understanding mechanism of action of potential therapeutic agents
• Experience with phenotypic testing, histology, IHC and protein expression analysis is required
• Ability to prioritize responsibilities to meet project deadlines and flexibility to react quickly to changing research needs
• Experience in other hypertension models and a willingness to learn about additional models
• Desire to be hands-on in the lab as well as the ability to work collaboratively in a cross-functional and team-based environment
• Excellent interpersonal oral and written communication skills?


How will you grow with us?

As a member of the Preclinical Pharmacology team, you will be able to apply your knowledge to significantly contribute to the advancement of our preclinical research efforts. Acceleron’s fast-paced environment and commitment to developing our employees will allow you to grow through hands-on experience with exciting projects. You will collaborate with our dynamic, multidisciplinary research team, learning from and supporting one another while working towards the common goal of transforming the lives of patients. Join our team!

In compliance with federal law, all persons hired will be required to verify identity and eligibility to work in the United States and complete the required employment eligibility verification document form upon hire.

*Recruiters - please do not send unsolicited resumes to this posting.

FOR IMMEDIATE CONSIDERATION PLEASE VISIT OUR WEBSITE AT:

www.acceleronpharma.com

APPLY FOR THIS JOB

Contact Person: Human Resources Recruitment
Email Address: recruitment@acceleronpharma.com
Apply URL: https://app.jobvite.com/j?cj=oCZl6fwM&s=MassBio

• Location: Boston, Cambridge, MA

• Post ID: 54451662 boston
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